关键词: 动物模型, 脾肾阳虚, 研究进展, 病证结合, CiteSpace

Abstract: The syndrome of yang deficiency of spleen and kidney is a common syndrome in traditional Chinese medicine, which is characterized by dull pain in the abdomen, diarrhea and loose stools, or even dawn diarrhea and so on. The replication of experimental animal model is an important means in basic research, but there is a lack of unified standard for the replication of animal model of spleen and kidney yang deficiency syndrome. This paper systematically summarizes the research on the animal model of spleen and kidney yang deficiency syndrome, and makes a visual analysis of the animal model of spleen and kidney yang deficiency syndrome based on CiteSpace software to reveal its research status, hot spots and trends. It is found that in recent years, the research on the animal model of yang deficiency of spleen and kidney has gradually increased, and rats are common model animals. The method of warming the kidney and invigorating the spleen (Sishen pill) is the key treatment of spleen and kidney yang deficiency syndrome,and thecombinationof diseaseandsyndrome is the focusof research.

Key words: animal model, yang deficiency of spleen and kidney, research progress, combination of diseaseandsyndrome, CiteSpace